EASEE-PEARL: A Long-Term Registry Observing EASEE® Therapy for Focal Epilepsy in Germany

By capturing treatment data in everyday clinical practice, the EASEE-PEARL study aims to provide valuable insights into the long-term efficacy, safety, and applicability of the EASEE® System in people with treatment-resistant focal epilepsy.

Patient Experiences at the Center

EASEE-PEARL captures important insights into the use of the EASEE® System and its impact on the everyday lives of people with focal epilepsy.

Evidence from Clinical Practice

EASEE-PEARL helps to further improve the long-term care of people with focal epilepsy through practice-based evidence from everyday clinical care.

Long-Term Data on EASEE® 

The study provides insights into the efficacy, tolerability, acceptance, and use of EASEE® over a period of three years.

The Study at a Glance

  • Indication: Drug-resistant focal epilepsy
  • Population: 135 adult patients aged 18 and older
  • Intervention: Treatment with the EASEE® System as part of routine clinical care
  • Study Design: Multicenter registry study in Germany
  • Objective: Evaluation of efficacy, tolerability, and long-term use of the EASEE® System in a real-world setting

Procedure

Inclusion

Patients who meet the indication for use of the EASEE® System

Baseline

Prospective and retrospective baseline

Implantation

Implantation of the EASEE® System in accordance with standard clinical care

Activation

Activation of stimulation approximately four weeks after implantation

Follow-up

Follow-up visits as part of routine care

Study End

Three years after Implantation

Clinical Expertise behind EASEE-PEARL

Prof. Dr. med. Bettina Schmitz

Head of the Department of Neurology

Stroke Unit and Berlin Epilepsy Center
Vivantes

Medical Care Center for Neurology

Interested in EASEE-PEARL?

For questions about EASEE-PEARL, the study team at Vivantes Klinikum is happy to help.

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