Two Years, Real Results: EASEE® Therapy Brings Lasting Relief to People with Drug-Resistant Epilepsy

For people living with drug-resistant epilepsies, every day can feel uncertain. But a newly published long-term study offers a powerful message of hope: our EASEE® system has demonstrated sustained effectiveness over two full years — with many patients experiencing fewer seizures, and some becoming completely seizure-free.

Conducted at leading epilepsy centers in Germany and Belgium, the study followed 33 adults with long-standing focal epilepsy. These individuals had previously tried an average of eight different medications — often without success. But with EASEE®, the story changed.

• 65.4% of participants saw their seizure frequency reduced by at least half
• Nearly 1 in 4 were seizure-free in the final month of treatment
• Over 80% continued therapy for the full two years — even through a device replacement

“This is more than a clinical milestone — it’s a life-changing breakthrough.” says Karl Stoklosa, CEO of Precisis. “Many of these patients are now able to rejoin daily life without the constant fear of the next seizure.”

A Gentle, Everyday Therapy with Powerful Impact

Unlike alternative cranial neuromodulation devices, EASEE® is a less invasive implant placed just beneath the scalp. It delivers targeted stimulation to the brain— without touching it physically. The therapy is designed to be discreet, reversible, and compatible with everyday life.

What sets EASEE® apart is its unique combination of two complementary stimulation strategies: direct-current like stimulation to stabilize brain activity, and high frequency pulses to counteract emerging seizure patterns. This dual approach aims to enhance therapeutic precision and effectiveness — all while remaining gentle and well-tolerated.

“We wanted to create a therapy that works not just in the clinic, but in real life,” says Stoklosa.

And it does. Patients in the study reported not only fewer seizures, but also stable or improved mood, energy, and quality of life. No serious side effects were observed during the two-year period.

A Smart Next Step when Medication is not enough

For many people with focal epilepsies — especially those who don’t respond to medication — treatment choices are often few, highly invasive, or come with significant side effects.

EASEE® offers a new path — one that’s effective, well-tolerated, and designed with patients in mind.

Read the full study in Epilepsia